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Resensitising proteasome inhibitor-resistant myeloma with sphingosine kinase 2 inhibition
The introduction of the proteasome inhibitor bortezomib into treatment regimens for myeloma has led to substantial improvement in patient survival. However, whilst bortezomib elicits initial responses in many myeloma patients, this haematological malignancy remains incurable due to the development o...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626806/ https://www.ncbi.nlm.nih.gov/pubmed/34826777 http://dx.doi.org/10.1016/j.neo.2021.11.009 |