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Metformin attenuates LPS-induced neuronal injury and cognitive impairments by blocking NF-κB pathway
BACKGROUND: Neuroinflammatory response is considered to be a high-risk factor for cognitive impairments in the brain. Lipopolysaccharides (LPS) is an endotoxin that induces acute inflammatory responses in injected bodies. However, the molecular mechanisms underlying LPS-associated cognitive impairme...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626880/ https://www.ncbi.nlm.nih.gov/pubmed/34836498 http://dx.doi.org/10.1186/s12868-021-00678-5 |