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The tumor immune microenvironment of primary and metastatic HER2− positive breast cancers utilizing gene expression and spatial proteomic profiling

BACKGROUND: The characterization of the immune component of the tumor microenvironment (TME) of human epidermal growth factor receptor 2 positive (HER2+) breast cancer has been limited. Molecular and spatial characterization of HER2+ TME of primary, recurrent, and metastatic breast tumors has the po...

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Detalles Bibliográficos
Autores principales: Schlam, Ilana, Church, Sarah E., Hether, Tyler D., Chaldekas, Krysta, Hudson, Briana M., White, Andrew M., Maisonet, Emily, Harris, Brent T., Swain, Sandra M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626906/
https://www.ncbi.nlm.nih.gov/pubmed/34838031
http://dx.doi.org/10.1186/s12967-021-03113-9