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Phospholipase A2 group IIA correlates with circulating high-density lipoprotein cholesterol and modulates cholesterol efflux possibly through regulation of PPAR-γ/LXR-α/ABCA1 in macrophages

BACKGROUND: Secretory phospholipase A2 group IIA (sPLA2-IIA) is an independent risk factor for cardiovascular disease, but its role on high-density lipoprotein cholesterol (HDL-C) level has not been clarified. The aim of the present study was to explore the association between circulating sPLA2-IIA...

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Detalles Bibliográficos
Autores principales: Liang, Ling, Xie, Qiang, Sun, Changqing, Wu, Yuanhui, Zhang, Wei, Li, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626914/
https://www.ncbi.nlm.nih.gov/pubmed/34838043
http://dx.doi.org/10.1186/s12967-021-03151-3