Cargando…
Phospholipase A2 group IIA correlates with circulating high-density lipoprotein cholesterol and modulates cholesterol efflux possibly through regulation of PPAR-γ/LXR-α/ABCA1 in macrophages
BACKGROUND: Secretory phospholipase A2 group IIA (sPLA2-IIA) is an independent risk factor for cardiovascular disease, but its role on high-density lipoprotein cholesterol (HDL-C) level has not been clarified. The aim of the present study was to explore the association between circulating sPLA2-IIA...
Autores principales: | Liang, Ling, Xie, Qiang, Sun, Changqing, Wu, Yuanhui, Zhang, Wei, Li, Weihua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626914/ https://www.ncbi.nlm.nih.gov/pubmed/34838043 http://dx.doi.org/10.1186/s12967-021-03151-3 |
Ejemplares similares
-
Sonodynamic therapy-induced foam cells apoptosis activates the phagocytic PPARγ-LXRα-ABCA1/ABCG1 pathway and promotes cholesterol efflux in advanced plaque
por: Wang, Huan, et al.
Publicado: (2018) -
EEPD1 Is a Novel LXR Target Gene in Macrophages Which Regulates ABCA1 Abundance and Cholesterol Efflux
por: Nelson, Jessica Kristine, et al.
Publicado: (2017) -
Cholesterol efflux is LXRα isoform-dependent in human macrophages
por: Ma, A Zhi Sha, et al.
Publicado: (2014) -
miR-206 controls LXRα expression and promotes LXR-mediated cholesterol efflux in macrophages
por: Vinod, Manjula, et al.
Publicado: (2014) -
Opuntia dillenii Haw. Polysaccharide Promotes Cholesterol Efflux in THP-1-Derived Foam Cells via the PPARγ-LXRα Signaling Pathway
por: Li, Heng, et al.
Publicado: (2022)