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Power calculator for detecting allelic imbalance using hierarchical Bayesian model

OBJECTIVE: Allelic imbalance (AI) is the differential expression of the two alleles in a diploid. AI can vary between tissues, treatments, and environments. Methods for testing AI exist, but methods are needed to estimate type I error and power for detecting AI and difference of AI between condition...

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Detalles Bibliográficos
Autores principales: Sherbina, Katrina, León-Novelo, Luis G., Nuzhdin, Sergey V., McIntyre, Lauren M., Marroni, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626927/
https://www.ncbi.nlm.nih.gov/pubmed/34838135
http://dx.doi.org/10.1186/s13104-021-05851-x