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PIAS3 suppresses damage in an Alzheimer’s disease cell model by inducing the STAT3-associated STAT3/Nestin/Nrf2/HO-1 pathway

BACKGROUND: Alzheimer’s disease (AD), the most common form of dementia, is caused by the degeneration of the central nervous system (CNS). A previous study reported that signal transducer and activator of transcription 3 (STAT3) is activated during AD development; nonetheless, the related mechanism...

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Detalles Bibliográficos
Autores principales: Li, Chen, Wang, Ruili, Zhang, Youyou, Hu, Chunting, Ma, Qiaoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626961/
https://www.ncbi.nlm.nih.gov/pubmed/34837964
http://dx.doi.org/10.1186/s10020-021-00410-3