A CRTH2 antagonist, CT-133, suppresses NF-κB signalling to relieve lipopolysaccharide-induced acute lung injury

Acute lung injury (ALI) and acute respiratory distress syndrome are life-threatening conditions that still have no definite pharmacotherapy. Hence, we investigate the potential effectiveness and underlying mechanism of CT-133, a newly developed selective antagonist of prostaglandin D2 receptor 2 (DP...

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Detalles Bibliográficos
Autores principales: Hussain, Musaddique, Xu, Chengyun, Wu, Xiling, Lu, Meiping, Tang, Lanfang, Wu, Fugen, Wu, Ximei, Wu, Junsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2019
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627115/
https://www.ncbi.nlm.nih.gov/pubmed/30951719
http://dx.doi.org/10.1016/j.ejphar.2019.03.053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627115/
https://www.ncbi.nlm.nih.gov/pubmed/30951719
http://dx.doi.org/10.1016/j.ejphar.2019.03.053

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