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Inhibition of Lipopolysaccharide-Induced Inflammatory Bone Loss by Saikosaponin D is Associated with Regulation of the RANKL/RANK Pathway

BACKGROUND: Osteolytic diseases such as osteoporosis are featured with accelerated osteoclast differentiation and strong bone resorption. Considering the complications and other limitations of current drug treatments, it is necessary to develop a safer and more reliable drug to deal with osteoclast-...

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Detalles Bibliográficos
Autores principales: Wu, Xinhui, Zhao, Kangxian, Fang, Xiaoxin, Lu, Feng, Zhang, Weikang, Song, Xiaoting, Chen, Lihua, Sun, Jiacheng, Chen, Haixiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627275/
https://www.ncbi.nlm.nih.gov/pubmed/34848946
http://dx.doi.org/10.2147/DDDT.S334421