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The Clinical Genetics of Hemophilia B (Factor IX Deficiency)

Hemophilia B (HB) is a bleeding disorder caused by deficiency of or defect in blood coagulation factor IX (FIX) inherited in an X-linked manner. It results from one of over 1000 known pathogenic variants in the FIX gene, F9; missense and frameshift changes predominate. Although primarily males are a...

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Detalles Bibliográficos
Autor principal: Miller, Connie H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627312/
https://www.ncbi.nlm.nih.gov/pubmed/34848993
http://dx.doi.org/10.2147/TACG.S288256