A Missense Variant in Granulysin is Associated with the Efficacy of Pegylated-Interferon-Alpha Therapy in Chinese Patients with HBeAg-Positive Chronic Hepatitis B

PURPOSE: Granulysin (GNLY) is a cytotoxic granule that has been reported to have various antimicrobial activities. We evaluated the association between a missense variant in GNLY (rs11127) and treatment efficacy of pegylated interferon-alpha (PegIFNα) or nucleos(t)ide analogs (NUCs) in patients with...

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Detalles Bibliográficos
Autores principales: Li, Jing, Chen, Haitao, Chen, Jiaxuan, Zhou, Bin, Hou, Jinlin, Jiang, De-Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627316/
https://www.ncbi.nlm.nih.gov/pubmed/34848996
http://dx.doi.org/10.2147/PGPM.S337962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627316/
https://www.ncbi.nlm.nih.gov/pubmed/34848996
http://dx.doi.org/10.2147/PGPM.S337962

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