Clinical and Prognostic Implications of 1p/19q, IDH, BRAF, MGMT Promoter, and TERT Promoter Alterations, and Expression of Ki-67 and p53 in Human Gliomas

BACKGROUND AND OBJECTIVE: Genetic alterations, including IDH, BRAF, and TERT promoter mutations (IDH-mu, BRAF-mu, TERTp-mu, respectively), 1p/19q co-deletion (1p/19q-codel), and MGMT promoter methylation (MGMTp-M), are correlated with glioma tumor development. Therefore, these genetic alterations co...

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Detalles Bibliográficos
Autores principales: Yang, Zixi, Ling, Feng, Ruan, Sibei, Hu, Jiajia, Tang, Mingxi, Sun, Xingwang, Long, Wenbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627377/
https://www.ncbi.nlm.nih.gov/pubmed/34849029
http://dx.doi.org/10.2147/CMAR.S336213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627377/
https://www.ncbi.nlm.nih.gov/pubmed/34849029
http://dx.doi.org/10.2147/CMAR.S336213

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