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Clinical and Prognostic Implications of 1p/19q, IDH, BRAF, MGMT Promoter, and TERT Promoter Alterations, and Expression of Ki-67 and p53 in Human Gliomas
BACKGROUND AND OBJECTIVE: Genetic alterations, including IDH, BRAF, and TERT promoter mutations (IDH-mu, BRAF-mu, TERTp-mu, respectively), 1p/19q co-deletion (1p/19q-codel), and MGMT promoter methylation (MGMTp-M), are correlated with glioma tumor development. Therefore, these genetic alterations co...
Autores principales: | Yang, Zixi, Ling, Feng, Ruan, Sibei, Hu, Jiajia, Tang, Mingxi, Sun, Xingwang, Long, Wenbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627377/ https://www.ncbi.nlm.nih.gov/pubmed/34849029 http://dx.doi.org/10.2147/CMAR.S336213 |
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