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Early-pregnancy prediction of risk for pre-eclampsia using maternal blood leptin/ceramide ratio: discovery and confirmation

OBJECTIVE: This study aimed to develop a blood test for the prediction of pre-eclampsia (PE) early in gestation. We hypothesised that the longitudinal measurements of circulating adipokines and sphingolipids in maternal serum over the course of pregnancy could identify novel prognostic biomarkers th...

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Detalles Bibliográficos
Autores principales: Huang, Qianyang, Hao, Shiying, You, Jin, Yao, Xiaoming, Li, Zhen, Schilling, James, Thyparambil, Sheeno, Liao, Wei-Li, Zhou, Xin, Mo, Lihong, Ladella, Subhashini, Davies-Balch, Shantay R, Zhao, Hangyi, Fan, David, Whitin, John C, Cohen, Harvey J, McElhinney, Doff B, Wong, Ronald J, Shaw, Gary M, Stevenson, David K, Sylvester, Karl G, Ling, Xuefeng B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627403/
https://www.ncbi.nlm.nih.gov/pubmed/34824115
http://dx.doi.org/10.1136/bmjopen-2021-050963