Cargando…

Early-pregnancy prediction of risk for pre-eclampsia using maternal blood leptin/ceramide ratio: discovery and confirmation

OBJECTIVE: This study aimed to develop a blood test for the prediction of pre-eclampsia (PE) early in gestation. We hypothesised that the longitudinal measurements of circulating adipokines and sphingolipids in maternal serum over the course of pregnancy could identify novel prognostic biomarkers th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Qianyang, Hao, Shiying, You, Jin, Yao, Xiaoming, Li, Zhen, Schilling, James, Thyparambil, Sheeno, Liao, Wei-Li, Zhou, Xin, Mo, Lihong, Ladella, Subhashini, Davies-Balch, Shantay R, Zhao, Hangyi, Fan, David, Whitin, John C, Cohen, Harvey J, McElhinney, Doff B, Wong, Ronald J, Shaw, Gary M, Stevenson, David K, Sylvester, Karl G, Ling, Xuefeng B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Obstetrics and Gynaecology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627403/ https://www.ncbi.nlm.nih.gov/pubmed/34824115 http://dx.doi.org/10.1136/bmjopen-2021-050963

Ejemplares similares

Maternal metabolic profiling to assess fetal gestational age and predict preterm delivery: a two-centre retrospective cohort study in the US
por: Sylvester, Karl G, et al.
Publicado: (2020)

Cohort profile: the Finnish Genetics of Pre-eclampsia Consortium (FINNPEC)
por: Jääskeläinen, Tiina, et al.
Publicado: (2016)

A five-year trend in pre-eclampsia admission and factors associated with inpatient eclampsia: a retrospective study from a resource-limited hospital in northeast Ethiopia
por: Tlaye, Kenean Getaneh, et al.
Publicado: (2021)

Open-labelled randomised controlled trial of 12 hours versus 24 hours modified Pritchard regimen in the management of eclampsia and pre-eclampsia in Ghana (MOPEP Study): study protocol
por: Beyuo, Titus, et al.
Publicado: (2019)

Machine learning models for predicting pre-eclampsia: a systematic review protocol
por: Ranjbar, Amene, et al.
Publicado: (2023)

Clinical features of isolated gestational proteinuria progressing to pre-eclampsia: retrospective observational study
por: Akaishi, Rina, et al.
Publicado: (2014)

Prospective assessment of neurodevelopment in children following a pregnancy complicated by severe pre-eclampsia
por: Warshafsky, Chelsie, et al.
Publicado: (2016)

Postpartum lifestyle interventions among women with pre-eclampsia: a scoping review protocol
por: Haugdahl, Hege Selnes, et al.
Publicado: (2020)

Cardiovascular and cerebrovascular health after pre-eclampsia: the Motherhealth prospective cohort study protocol
por: Miller, Eliza C, et al.
Publicado: (2021)

Is urinary excretion of plasminogen associated with development of pre-eclampsia? An observational, explorative case–control study
por: Nielsen, Lise H, et al.
Publicado: (2019)

Aspirin and heparin for the prevention of pre-eclampsia: protocol for a systematic review and network meta-analysis
por: Huang, Jinzhu, et al.
Publicado: (2019)

Insufficient iodine nutrition status and the risk of pre-eclampsia: a systemic review and meta-analysis
por: Businge, Charles Bitamazire, et al.
Publicado: (2021)

Prevalence and risk of pre-eclampsia and gestational hypertension in twin pregnancies: a population-based register study
por: Laine, Katariina, et al.
Publicado: (2019)

Insufficient iodine nutrition status and the risk of pre-eclampsia: a protocol for systematic review and meta-analysis
por: Businge, Charles Bitamazire, et al.
Publicado: (2019)

Understanding challenges as they impact on hospital-level care for pre-eclampsia in rural Ethiopia: a qualitative study
por: Robbins, Tanya, et al.
Publicado: (2023)

Double blind, randomised, placebo-controlled trial to evaluate the efficacy of esomeprazole to treat early onset pre-eclampsia (PIE Trial): a study protocol
por: Cluver, Catherine A, et al.
Publicado: (2015)

A double blind, randomised, placebo-controlled trial to evaluate the efficacy of metformin to treat preterm pre-eclampsia (PI2 Trial): study protocol
por: Cluver, Catherine, et al.
Publicado: (2019)

Patient journey during and after a pre-eclampsia-complicated pregnancy: a cross-sectional patient registry study
por: Bijl, Rianne C, et al.
Publicado: (2022)

Pre-eclampsia and cardiovascular risk: a long-term nationwide cohort study on over 120 000 Finnish women
por: Venetkoski, Minttu, et al.
Publicado: (2022)

Use of antihistamines before or during pregnancy and risk of early-onset pre-eclampsia in allergic women: a population-based cohort study
por: Sande, Anne K, et al.
Publicado: (2022)

Calcium supplementation to prevent pre-eclampsia: protocol for an individual participant data meta-analysis, network meta-analysis and health economic evaluation
por: Rocha, Thaís, et al.
Publicado: (2023)

Community engagement for birth preparedness and complication readiness in the Community Level Interventions for Pre-eclampsia (CLIP) Trial in India: a mixed-method evaluation
por: Kavi, Avinash, et al.
Publicado: (2022)

Low-dose aspirin for preventing intrauterine growth restriction and pre-eclampsia in sickle cell pregnancy (PIPSICKLE): a randomised controlled trial (study protocol)
por: Afolabi, Bosede Bukola, et al.
Publicado: (2021)

Association between hypoproteinaemia with massive proteinuria and small for gestational age in pre-eclampsia: a single-centre, retrospective cohort study using propensity score matching
por: Lv, Yanxiang, et al.
Publicado: (2023)

Phase I pilot clinical trial of antenatal maternally administered melatonin to decrease the level of oxidative stress in human pregnancies affected by pre-eclampsia (PAMPR): study protocol
por: Hobson, Sebastian R, et al.
Publicado: (2013)

First trimester screening for pre-eclampsia and intrauterine growth restriction using three-dimensional Doppler angiography (SPIRIT): protocol for a multicentre prospective study in nulliparous pregnant women
por: Bertholdt, Charline, et al.
Publicado: (2020)

Trial of feasibility and acceptability of routine low-dose aspirin versus Early Screening Test indicated aspirin for pre-eclampsia prevention (TEST study): a multicentre randomised controlled trial
por: Mone, Fionnuala, et al.
Publicado: (2018)

PARROT Ireland: Placental growth factor in Assessment of women with suspected pre-eclampsia to reduce maternal morbidity: a Stepped Wedge Cluster Randomised Control Trial Research Study Protocol
por: Hayes-Ryan, Deirdre, et al.
Publicado: (2019)

Effectiveness and safety of 1 vs 4 h blood pressure profile with clinical and laboratory assessment for the exclusion of gestational hypertension and pre-eclampsia: a retrospective study in a university affiliated maternity hospital
por: McCarthy, Elizabeth Anne, et al.
Publicado: (2015)

Racial and Ethnic Disparities in Anemia and Severe Maternal Morbidity
por: Igbinosa, Irogue I., et al.
Publicado: (2023)

Development of a Urine Metabolomics Biomarker-Based Prediction Model for Preeclampsia during Early Pregnancy
por: Zhang, Yaqi, et al.
Publicado: (2023)

Ectopic pregnancy: exploration of its global research architecture using density-equalising mapping and socioeconomic benchmarks
por: Brüggmann, Dörthe, et al.
Publicado: (2017)

Is maternity care in Scotland equitable? Results of a national maternity care survey
por: Cheyne, Helen, et al.
Publicado: (2019)

Population-based trends in pregnancy hypertension and pre-eclampsia: an international comparative study
por: Roberts, Christine L, et al.
Publicado: (2011)

Access to mass media and teenage pregnancy among adolescents in Zambia: a national cross-sectional survey
por: Sserwanja, Quraish, et al.
Publicado: (2022)

Serum levels of endothelial glycocalyx constituents in women at 20 weeks' gestation who later develop gestational diabetes mellitus compared to matched controls: a pilot study
por: Long, David S, et al.
Publicado: (2016)

Characteristics of women who practice yoga in different locations during pregnancy
por: Cramer, Holger, et al.
Publicado: (2015)

Maternal and perinatal outcomes by planned place of birth in Australia 2000 – 2012: a linked population data study
por: Homer, Caroline S E, et al.
Publicado: (2019)

Awareness of cervical cancer among women attending an HIV treatment centre: a cross-sectional study from Morocco
por: Belglaiaa, Essaada, et al.
Publicado: (2018)

‘connEcted caesarean section’: creating a virtual link between MOthers and their infanTs to ImprOve maternal childbirth experieNce – study protocol for a PILOT trial (e-motion-pilot)
por: Corbaz, Fiona, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_mt8vseoe9usr2ack922sftt7sm