Initiation of hepatic stellate cell activation extends into chronic liver disease

Activated hepatic stellate cells (aHSC) are the main source of extra cellular matrix in liver fibrosis. Activation is classically divided in two phases: initiation and perpetuation. Currently, HSC-based therapeutic candidates largely focus on targeting the aHSCs in the perpetuation phase. However, t...

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Detalles Bibliográficos
Autores principales: De Smet, Vincent, Eysackers, Nathalie, Merens, Vincent, Kazemzadeh Dastjerd, Mina, Halder, Georg, Verhulst, Stefaan, Mannaerts, Inge, van Grunsven, Leo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627507/
https://www.ncbi.nlm.nih.gov/pubmed/34839349
http://dx.doi.org/10.1038/s41419-021-04377-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627507/
https://www.ncbi.nlm.nih.gov/pubmed/34839349
http://dx.doi.org/10.1038/s41419-021-04377-1

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