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His domain protein tyrosine phosphatase and Rabaptin-5 couple endo-lysosomal sorting of EGFR with endosomal maturation

His domain protein tyrosine phosphatase (HD-PTP; also known as PTPN23) collaborates with endosomal sorting complexes required for transport (ESCRTs) to sort endosomal cargo into intralumenal vesicles, forming the multivesicular body (MVB). Completion of MVB sorting is accompanied by maturation of th...

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Detalles Bibliográficos
Autores principales: Parkinson, Gabrielle, Roboti, Peristera, Zhang, Ling, Taylor, Sandra, Woodman, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627557/
https://www.ncbi.nlm.nih.gov/pubmed/34657963
http://dx.doi.org/10.1242/jcs.259192