Alveolar progenitor differentiation and lactation depends on paracrine inhibition of notch via ROBO1/CTNNB1/JAG1

In the mammary gland, how alveolar progenitor cells are recruited to fuel tissue growth with each estrus cycle and pregnancy remains poorly understood. Here, we identify a regulatory pathway that controls alveolar progenitor differentiation and lactation by governing Notch activation in mouse. Loss...

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Detalles Bibliográficos
Autores principales: Cazares, Oscar, Chatterjee, Sharmila, Lee, Pinky, Strietzel, Catherine, Bubolz, J. W., Harburg, Gwyndolen, Howard, Jon, Katzman, Sol, Sanford, Jeremy, Hinck, Lindsay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627605/
https://www.ncbi.nlm.nih.gov/pubmed/34758082
http://dx.doi.org/10.1242/dev.199940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627605/
https://www.ncbi.nlm.nih.gov/pubmed/34758082
http://dx.doi.org/10.1242/dev.199940

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