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Palmitic acid causes increased dihydroceramide levels when desaturase expression is directly silenced or indirectly lowered by silencing AdipoR2

BACKGROUND: AdipoR1 and AdipoR2 (AdipoRs) are plasma membrane proteins often considered to act as adiponectin receptors with a ceramidase activity. Additionally, the AdipoRs and their yeast and C. elegans orthologs are emerging as membrane homeostasis regulators that counter membrane rigidification...

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Detalles Bibliográficos
Autores principales: Ruiz, Mario, Henricsson, Marcus, Borén, Jan, Pilon, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627610/
https://www.ncbi.nlm.nih.gov/pubmed/34839823
http://dx.doi.org/10.1186/s12944-021-01600-y