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Palmitic acid causes increased dihydroceramide levels when desaturase expression is directly silenced or indirectly lowered by silencing AdipoR2
BACKGROUND: AdipoR1 and AdipoR2 (AdipoRs) are plasma membrane proteins often considered to act as adiponectin receptors with a ceramidase activity. Additionally, the AdipoRs and their yeast and C. elegans orthologs are emerging as membrane homeostasis regulators that counter membrane rigidification...
Autores principales: | Ruiz, Mario, Henricsson, Marcus, Borén, Jan, Pilon, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627610/ https://www.ncbi.nlm.nih.gov/pubmed/34839823 http://dx.doi.org/10.1186/s12944-021-01600-y |
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