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Attenuation of apoptotic cell detection triggers thymic regeneration after damage

The thymus, which is the primary site of T cell development, is particularly sensitive to insult but also has a remarkable capacity for repair. However, the mechanisms orchestrating regeneration are poorly understood, and delayed repair is common after cytoreductive therapies. Here, we demonstrate a...

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Detalles Bibliográficos
Autores principales: Kinsella, Sinéad, Evandy, Cindy A., Cooper, Kirsten, Iovino, Lorenzo, deRoos, Paul C., Hopwo, Kayla S., Granadier, David W., Smith, Colton W., Rafii, Shahin, Dudakov, Jarrod A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627669/
https://www.ncbi.nlm.nih.gov/pubmed/34610317
http://dx.doi.org/10.1016/j.celrep.2021.109789