In vitro and in vivo activity of GT-1, a novel siderophore cephalosporin, and GT-055, a broad-spectrum β-lactamase inhibitor, against biothreat and ESKAPE pathogens

Antimicrobial-resistance (AMR) has become an increasingly difficult issue to overcome for bacteria associated with both community- and hospital-acquired infections as well as potential biodefense threats. The need to identify new therapeutics of novel classes and/or with unique mechanisms is critica...

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Detalles Bibliográficos
Autores principales: Halasohoris, Stephanie A., Scarff, Jennifer M., Pysz, Lisa M., Lembirik, Sanae, Lemmon, Margaret M., Biek, Donald, Hannah, Brendan, Zumbrun, Steven D., Panchal, Rekha G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627911/
https://www.ncbi.nlm.nih.gov/pubmed/34522025
http://dx.doi.org/10.1038/s41429-021-00472-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627911/
https://www.ncbi.nlm.nih.gov/pubmed/34522025
http://dx.doi.org/10.1038/s41429-021-00472-9

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