Interactions between nascent proteins and the ribosome surface inhibit co-translational folding

Most proteins begin to fold during biosynthesis on the ribosome. It has been suggested that interactions between the emerging polypeptide and the ribosome surface might allow the ribosome itself to modulate co-translational folding. Here we combine protein engineering and NMR spectroscopy to charact...

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Detalles Bibliográficos
Autores principales: Cassaignau, Anaïs M. E., Włodarski, Tomasz, Chan, Sammy H. S., Woodburn, Lauren F., Bukvin, Ivana V., Streit, Julian O., Cabrita, Lisa D., Waudby, Christopher A., Christodoulou, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627912/
https://www.ncbi.nlm.nih.gov/pubmed/34650236
http://dx.doi.org/10.1038/s41557-021-00796-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627912/
https://www.ncbi.nlm.nih.gov/pubmed/34650236
http://dx.doi.org/10.1038/s41557-021-00796-x

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