A novel peroxisome proliferator-activated receptor gamma ligand improves insulin sensitivity and promotes browning of white adipose tissue in obese mice

OBJECTIVE: Nuclear receptor Peroxisome Proliferator-Activated Receptor γ (PPARγ) is a promising target for the treatment of type 2 diabetes. The antidiabetic drug thiazolidinediones (TZDs) are potent insulin sensitizers as full agonists of PPARγ, but cause unwanted side effects. Recent discoveries h...

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Detalles Bibliográficos
Autores principales: Wu, Dan, Eeda, Venkateswararao, Undi, Ram Babu, Mann, Shivani, Stout, Michael, Lim, Hui-Ying, Wang, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627988/
https://www.ncbi.nlm.nih.gov/pubmed/34710641
http://dx.doi.org/10.1016/j.molmet.2021.101363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8627988/
https://www.ncbi.nlm.nih.gov/pubmed/34710641
http://dx.doi.org/10.1016/j.molmet.2021.101363

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