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Input-dependent synaptic suppression by pregabalin in the central amygdala in male mice with inflammatory pain

Pregabalin (PGB) is a synthetic amino acid compound most widely prescribed for chronic peripheral and central neuropathic pain. PGB is a ligand for the α(2)δ(1) subunit of voltage-dependent calcium channels, and its binding reduces neurotransmitter release and thus inhibits synaptic transmission. Th...

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Detalles Bibliográficos
Autores principales: Yamamoto, Sumii, Takahashi, Yukari, Kato, Fusao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628014/
https://www.ncbi.nlm.nih.gov/pubmed/34877437
http://dx.doi.org/10.1016/j.ynpai.2021.100078