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Input-dependent synaptic suppression by pregabalin in the central amygdala in male mice with inflammatory pain
Pregabalin (PGB) is a synthetic amino acid compound most widely prescribed for chronic peripheral and central neuropathic pain. PGB is a ligand for the α(2)δ(1) subunit of voltage-dependent calcium channels, and its binding reduces neurotransmitter release and thus inhibits synaptic transmission. Th...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628014/ https://www.ncbi.nlm.nih.gov/pubmed/34877437 http://dx.doi.org/10.1016/j.ynpai.2021.100078 |