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Molecular and structural basis of olfactory sensory neuron axon coalescence by Kirrel receptors

Projections from sensory neurons of olfactory systems coalesce into glomeruli in the brain. The Kirrel receptors are believed to homodimerize via their ectodomains and help separate sensory neuron axons into Kirrel2- or Kirrel3-expressing glomeruli. Here, we present the crystal structures of homodim...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Vaddadi, Neelima, Pak, Joseph S., Park, Yeonwoo, Quilez, Sabrina, Roman, Christina A., Dumontier, Emilie, Thornton, Joseph W., Cloutier, Jean-François, Özkan, Engin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628261/
https://www.ncbi.nlm.nih.gov/pubmed/34731636
http://dx.doi.org/10.1016/j.celrep.2021.109940