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Molecular and structural basis of olfactory sensory neuron axon coalescence by Kirrel receptors
Projections from sensory neurons of olfactory systems coalesce into glomeruli in the brain. The Kirrel receptors are believed to homodimerize via their ectodomains and help separate sensory neuron axons into Kirrel2- or Kirrel3-expressing glomeruli. Here, we present the crystal structures of homodim...
Autores principales: | Wang, Jing, Vaddadi, Neelima, Pak, Joseph S., Park, Yeonwoo, Quilez, Sabrina, Roman, Christina A., Dumontier, Emilie, Thornton, Joseph W., Cloutier, Jean-François, Özkan, Engin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628261/ https://www.ncbi.nlm.nih.gov/pubmed/34731636 http://dx.doi.org/10.1016/j.celrep.2021.109940 |
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