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Evolution of the folding landscape of effector caspases

Caspases are a family of cysteinyl proteases that control programmed cell death and maintain homeostasis in multicellular organisms. The caspase family is an excellent model to study protein evolution because all caspases are produced as zymogens (procaspases [PCPs]) that must be activated to gain f...

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Detalles Bibliográficos
Autores principales: Shrestha, Suman, Clark, A. Clay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628267/
https://www.ncbi.nlm.nih.gov/pubmed/34592312
http://dx.doi.org/10.1016/j.jbc.2021.101249