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ScLRTC: imputation for single-cell RNA-seq data via low-rank tensor completion

BACKGROUND: With single-cell RNA sequencing (scRNA-seq) methods, gene expression patterns at the single-cell resolution can be revealed. But as impacted by current technical defects, dropout events in scRNA-seq lead to missing data and noise in the gene-cell expression matrix and adversely affect do...

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Detalles Bibliográficos
Autores principales: Pan, Xiutao, Li, Zhong, Qin, Shengwei, Yu, Minzhe, Hu, Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628418/
https://www.ncbi.nlm.nih.gov/pubmed/34844559
http://dx.doi.org/10.1186/s12864-021-08101-3