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Cenerimod, a selective S1P(1) receptor modulator, improves organ-specific disease outcomes in animal models of Sjögren’s syndrome

BACKGROUND: Sjögren’s syndrome is a systemic autoimmune disease characterized by immune cells predominantly infiltrating the exocrine glands and frequently forming ectopic lymphoid structures. These structures drive a local functional immune response culminating in autoantibody production and tissue...

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Detalles Bibliográficos
Autores principales: Gerossier, Estelle, Nayar, Saba, Froidevaux, Sylvie, Smith, Charlotte G., Runser, Celine, Iannizzotto, Valentina, Vezzali, Enrico, Pierlot, Gabin, Mentzel, Ulrich, Murphy, Mark J., Martinic, Marianne M., Barone, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628476/
https://www.ncbi.nlm.nih.gov/pubmed/34839819
http://dx.doi.org/10.1186/s13075-021-02673-x