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Glycoengineering of Therapeutic Antibodies with Small Molecule Inhibitors

Monoclonal antibodies (mAbs) are one of the cornerstones of modern medicine, across an increasing range of therapeutic areas. All therapeutic mAbs are glycoproteins, i.e., their polypeptide chain is decorated with glycans, oligosaccharides of extraordinary structural diversity. The presence, absence...

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Detalles Bibliográficos
Autores principales: Li, Shasha, McCraw, Alex J., Gardner, Richard A., Spencer, Daniel I.R., Karagiannis, Sophia N., Wagner, Gerd K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628514/
https://www.ncbi.nlm.nih.gov/pubmed/34842612
http://dx.doi.org/10.3390/antib10040044