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Increasing the sensitivity of hyperpolarized [(15)N(2)]urea detection by serial transfer of polarization to spin‐coupled protons
PURPOSE: Hyperpolarized (15)N‐labeled molecules have been proposed as imaging agents for investigating tissue perfusion and pH. However, the sensitivity of direct (15)N detection is limited by the isotope's low gyromagnetic ratio. Sensitivity can be increased by transferring (15)N hyperpolariza...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629126/ https://www.ncbi.nlm.nih.gov/pubmed/32153046 http://dx.doi.org/10.1002/mrm.28241 |