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Polyvinyl alcohol hydrolysis rate and molecular weight influence human and murine HSC activity ex vivo

Ex vivo expansion of hematopoietic stem cells (HSCs) is one of the most promising strategies to increase the availability of transplantable HSCs and improve bone marrow transplantation outcomes. We recently demonstrated that mouse HSCs could be efficiently expanded in polyvinyl alcohol (PVA)-contain...

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Detalles Bibliográficos
Autores principales: Sudo, Kazuhiro, Yamazaki, Satoshi, Wilkinson, Adam C., Nakauchi, Hiromitsu, Nakamura, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629160/
https://www.ncbi.nlm.nih.gov/pubmed/34509158
http://dx.doi.org/10.1016/j.scr.2021.102531