Gene expression signatures as candidate biomarkers of response to PD-1 blockade in non-small cell lung cancers

Although anti-PD-1/PD-L1 monotherapy has achieved clinical success in non-small cell lung cancer (NSCLC), definitive predictive biomarkers remain to be elucidated. In this study, we performed whole-transcriptome sequencing of pretreatment tumor tissue samples and pretreatment and on-treatment whole...

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Detalles Bibliográficos
Autores principales: Aiba, Tomoiki, Hattori, Chieko, Sugisaka, Jun, Shimizu, Hisashi, Ono, Hirotaka, Domeki, Yutaka, Saito, Ryohei, Kawana, Sachiko, Kawashima, Yosuke, Terayama, Keisuke, Toi, Yukihiro, Nakamura, Atsushi, Yamanda, Shinsuke, Kimura, Yuichiro, Suzuki, Yutaka, Niida, Atsushi, Sugawara, Shunichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629226/
https://www.ncbi.nlm.nih.gov/pubmed/34843570
http://dx.doi.org/10.1371/journal.pone.0260500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629226/
https://www.ncbi.nlm.nih.gov/pubmed/34843570
http://dx.doi.org/10.1371/journal.pone.0260500

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