Aldo-ketoreductase 1c19 ablation does not affect insulin secretion in murine islets

Beta cell failure is a critical feature of diabetes. It includes defects of insulin production, secretion, and altered numbers of hormone-producing cells. In previous work, we have shown that beta cell failure is mechanistically linked to loss of Foxo1 function. This loss of function likely results...

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Detalles Bibliográficos
Autores principales: Miyachi, Yasutaka, Kuo, Taiyi, Son, Jinsook, Accili, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629236/
https://www.ncbi.nlm.nih.gov/pubmed/34843575
http://dx.doi.org/10.1371/journal.pone.0260526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629236/
https://www.ncbi.nlm.nih.gov/pubmed/34843575
http://dx.doi.org/10.1371/journal.pone.0260526

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