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Aldo-ketoreductase 1c19 ablation does not affect insulin secretion in murine islets
Beta cell failure is a critical feature of diabetes. It includes defects of insulin production, secretion, and altered numbers of hormone-producing cells. In previous work, we have shown that beta cell failure is mechanistically linked to loss of Foxo1 function. This loss of function likely results...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629236/ https://www.ncbi.nlm.nih.gov/pubmed/34843575 http://dx.doi.org/10.1371/journal.pone.0260526 |