Variant profiling of colorectal adenomas from three patients of two families with MSH3-related adenomatous polyposis

The spectrum of somatic genetic variation in colorectal adenomas caused by biallelic pathogenic germline variants in the MSH3 gene, was comprehensively analysed to characterise mutational signatures and identify potential driver genes and pathways of MSH3-related tumourigenesis. Three patients from...

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Detalles Bibliográficos
Autores principales: Perne, Claudia, Peters, Sophia, Cartolano, Maria, Horpaopan, Sukanya, Grimm, Christina, Altmüller, Janine, Sommer, Anna K., Hillmer, Axel M., Thiele, Holger, Odenthal, Margarete, Möslein, Gabriela, Adam, Ronja, Sivalingam, Sugirthan, Kirfel, Jutta, Schweiger, Michal R., Peifer, Martin, Spier, Isabel, Aretz, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629245/
https://www.ncbi.nlm.nih.gov/pubmed/34843512
http://dx.doi.org/10.1371/journal.pone.0259185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629245/
https://www.ncbi.nlm.nih.gov/pubmed/34843512
http://dx.doi.org/10.1371/journal.pone.0259185

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