The effect of spironolactone on cardiac and renal fibrosis following myocardial infarction in established hypertension in the transgenic Cyp1a1Ren2 rat

AIMS: The renin-angiotensin-aldosterone axis plays a key role in mediating cardiac and kidney injury. Mineralocorticoid receptor antagonism has beneficial effects on cardiac dysfunction, but effects are less well quantified in the cardiorenal syndrome. This study investigated cardiac and kidney path...

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Detalles Bibliográficos
Autores principales: Leader, C. J., Wilkins, G. T., Walker, R. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629264/
https://www.ncbi.nlm.nih.gov/pubmed/34843581
http://dx.doi.org/10.1371/journal.pone.0260554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629264/
https://www.ncbi.nlm.nih.gov/pubmed/34843581
http://dx.doi.org/10.1371/journal.pone.0260554

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