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Amyotrophic lateral sclerosis: Correlations between fluid biomarkers of NfL, TDP-43, and tau, and clinical characteristics

OBJECTIVES: We previously reported the diagnostic and prognostic performance of neurofilament light chain (NfL), TAR DNA-binding protein 43 (TDP-43), and total tau (t-tau) in cerebrospinal fluid (CSF) and plasma as amyotrophic lateral sclerosis (ALS) biomarkers. The present study aimed to elucidate...

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Detalles Bibliográficos
Autores principales: Kojima, Yuta, Kasai, Takashi, Noto, Yu-ichi, Ohmichi, Takuma, Tatebe, Harutsugu, Kitaoji, Takamasa, Tsuji, Yukiko, Kitani-Morii, Fukiko, Shinomoto, Makiko, Allsop, David, Teramukai, Satoshi, Mizuno, Toshiki, Tokuda, Takahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629269/
https://www.ncbi.nlm.nih.gov/pubmed/34843548
http://dx.doi.org/10.1371/journal.pone.0260323