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JNK and Yorkie drive tumor malignancy by inducing L-amino acid transporter 1 in Drosophila

Identifying a common oncogenesis pathway among tumors with different oncogenic mutations is critical for developing anti-cancer strategies. Here, we performed transcriptome analyses on two different models of Drosophila malignant tumors caused by Ras activation with cell polarity defects (Ras(V12)/s...

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Detalles Bibliográficos
Autores principales: Cong, Bojie, Nakamura, Mai, Sando, Yukari, Kondo, Takefumi, Ohsawa, Shizue, Igaki, Tatsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629376/
https://www.ncbi.nlm.nih.gov/pubmed/34780467
http://dx.doi.org/10.1371/journal.pgen.1009893