Cargando…
JNK and Yorkie drive tumor malignancy by inducing L-amino acid transporter 1 in Drosophila
Identifying a common oncogenesis pathway among tumors with different oncogenic mutations is critical for developing anti-cancer strategies. Here, we performed transcriptome analyses on two different models of Drosophila malignant tumors caused by Ras activation with cell polarity defects (Ras(V12)/s...
Autores principales: | Cong, Bojie, Nakamura, Mai, Sando, Yukari, Kondo, Takefumi, Ohsawa, Shizue, Igaki, Tatsushi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629376/ https://www.ncbi.nlm.nih.gov/pubmed/34780467 http://dx.doi.org/10.1371/journal.pgen.1009893 |
Ejemplares similares
-
Epithelial cell-turnover ensures robust coordination of tissue growth in Drosophila ribosomal protein mutants
por: Akai, Nanami, et al.
Publicado: (2021) -
JNK-mediated Slit-Robo signaling facilitates epithelial wound repair by extruding dying cells
por: Iida, Chiaki, et al.
Publicado: (2019) -
Cell-cell interactions that drive tumorigenesis in Drosophila
por: Enomoto, Masato, et al.
Publicado: (2022) -
Notch Inhibits Yorkie Activity in Drosophila Wing Discs
por: Djiane, Alexandre, et al.
Publicado: (2014) -
Notch Signaling Activates Yorkie Non-Cell Autonomously in Drosophila
por: Graves, Hillary K., et al.
Publicado: (2012)