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Regional and temporal heterogeneity of epithelial ovarian cancer tumor biopsies: implications for therapeutic strategies

Stage III/IV epithelial ovarian cancer (EOC) is a systemic disease. The clonal relationship among different tumor lesions at diagnosis (spatial heterogeneity) and how tumor clonal architecture evolves over time (temporal heterogeneity) have not yet been defined. Such knowledge would help to develop...

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Detalles Bibliográficos
Autores principales: Paracchini, Lara, Mannarino, Laura, Craparotta, Ilaria, Romualdi, Chiara, Fruscio, Robert, Grassi, Tommaso, Fotia, Vittoria, Caratti, Giulia, Perego, Patrizia, Calura, Enrica, Clivio, Luca, D’Incalci, Maurizio, Beltrame, Luca, Marchini, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629406/
https://www.ncbi.nlm.nih.gov/pubmed/34853661
http://dx.doi.org/10.18632/oncotarget.10505