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Regional and temporal heterogeneity of epithelial ovarian cancer tumor biopsies: implications for therapeutic strategies
Stage III/IV epithelial ovarian cancer (EOC) is a systemic disease. The clonal relationship among different tumor lesions at diagnosis (spatial heterogeneity) and how tumor clonal architecture evolves over time (temporal heterogeneity) have not yet been defined. Such knowledge would help to develop...
Autores principales: | Paracchini, Lara, Mannarino, Laura, Craparotta, Ilaria, Romualdi, Chiara, Fruscio, Robert, Grassi, Tommaso, Fotia, Vittoria, Caratti, Giulia, Perego, Patrizia, Calura, Enrica, Clivio, Luca, D’Incalci, Maurizio, Beltrame, Luca, Marchini, Sergio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629406/ https://www.ncbi.nlm.nih.gov/pubmed/34853661 http://dx.doi.org/10.18632/oncotarget.10505 |
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