Loss of sister kinetochore co-orientation and peri-centromeric cohesin protection after meiosis I depends on cleavage of centromeric REC8

Protection of peri-centromeric (periCEN) REC8 cohesin from Separase and sister kinetochore (KT) attachment to microtubules emanating from the same spindle pole (co-orientation) ensures that sister chromatids remain associated after meiosis I. Both features are lost during meiosis II, resulting in si...

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Detalles Bibliográficos
Autores principales: Ogushi, Sugako, Rattani, Ahmed, Godwin, Jonathan, Metson, Jean, Schermelleh, Lothar, Nasmyth, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629431/
https://www.ncbi.nlm.nih.gov/pubmed/34758289
http://dx.doi.org/10.1016/j.devcel.2021.10.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629431/
https://www.ncbi.nlm.nih.gov/pubmed/34758289
http://dx.doi.org/10.1016/j.devcel.2021.10.017

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