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Kinetochore life histories reveal an Aurora-B-dependent error correction mechanism in anaphase
Chromosome mis-segregation during mitosis leads to aneuploidy, which is a hallmark of cancer and linked to cancer genome evolution. Errors can manifest as “lagging chromosomes” in anaphase, although their mechanistic origins and likelihood of correction are incompletely understood. Here, we combine...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629432/ https://www.ncbi.nlm.nih.gov/pubmed/34758290 http://dx.doi.org/10.1016/j.devcel.2021.10.007 |