Pemafibrate, A Novel Selective Peroxisome Proliferator-Activated Receptor α Modulator, Reduces Plasma Eicosanoid Levels and Ameliorates Endothelial Dysfunction in Diabetic Mice

Aims: Various pathological processes related to diabetes cause endothelial dysfunction. Eicosanoids derived from arachidonic acid (AA) have roles in vascular regulation. Fibrates have recently been shown to attenuate vascular complications in diabetics. Here we examined the effects of pemafibrate, a...

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Detalles Bibliográficos
Autores principales: Suto, Kumiko, Fukuda, Daiju, Shinohara, Masakazu, Ganbaatar, Byambasuren, Yagi, Shusuke, Kusunose, Kenya, Yamada, Hirotsugu, Soeki, Takeshi, Hirata, Ken-ichi, Sata, Masataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Atherosclerosis Society 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629704/
https://www.ncbi.nlm.nih.gov/pubmed/33775978
http://dx.doi.org/10.5551/jat.61101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629704/
https://www.ncbi.nlm.nih.gov/pubmed/33775978
http://dx.doi.org/10.5551/jat.61101

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