Tasimelteon safely and effectively improves sleep in Smith–Magenis syndrome: a double-blind randomized trial followed by an open-label extension

PURPOSE: To assess the efficacy of tasimelteon to improve sleep in Smith–Magenis syndrome (SMS). METHODS: A 9-week, double-blind, randomized, two-period crossover study was conducted at four US clinical centers. Genetically confirmed patients with SMS, aged 3 to 39, with sleep complaints participate...

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Detalles Bibliográficos
Autores principales: Polymeropoulos, Christos M., Brooks, Justin, Czeisler, Emily L., Fisher, Michaela A., Gibson, Mary M., Kite, Kailey, Smieszek, Sandra P., Xiao, Changfu, Elsea, Sarah H., Birznieks, Gunther, Polymeropoulos, Mihael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629754/
https://www.ncbi.nlm.nih.gov/pubmed/34316024
http://dx.doi.org/10.1038/s41436-021-01282-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629754/
https://www.ncbi.nlm.nih.gov/pubmed/34316024
http://dx.doi.org/10.1038/s41436-021-01282-y

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