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Safety and efficacy of ampreloxetine in symptomatic neurogenic orthostatic hypotension: a phase 2 trial

PURPOSE: In neurogenic orthostatic hypotension, blood pressure falls when upright owing to impaired release of norepinephrine, leading to dizziness. Ampreloxetine, a selective norepinephrine reuptake inhibitor, increases circulating norepinephrine levels. This study explored the safety of ampreloxet...

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Detalles Bibliográficos
Autores principales: Kaufmann, Horacio, Vickery, Ross, Wang, Whedy, Kanodia, Jitendra, Shibao, Cyndya A., Norcliffe-Kaufmann, Lucy, Haumann, Brett, Biaggioni, Italo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629777/
https://www.ncbi.nlm.nih.gov/pubmed/34657222
http://dx.doi.org/10.1007/s10286-021-00827-0