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Apoptosis resistance of senescent cells is an intrinsic barrier for senolysis induced by cardiac glycosides
Targeted elimination of senescent cells, senolysis, is one of the core trends in the anti-aging therapy. Cardiac glycosides were recently proved to be a broad-spectrum senolytics. Here we tested senolytic properties of cardiac glycosides towards human mesenchymal stem cells (hMSCs). Cardiac glycosid...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629786/ https://www.ncbi.nlm.nih.gov/pubmed/34714358 http://dx.doi.org/10.1007/s00018-021-03980-x |