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Kappa but not delta or mu opioid receptors form homodimers at low membrane densities

Opioid receptors (ORs) have been observed as homo- and heterodimers, but it is unclear if the dimers are stable under physiological conditions, and whether monomers or dimers comprise the predominant fraction in a cell. Here, we use three live-cell imaging approaches to assess dimerization of ORs at...

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Detalles Bibliográficos
Autores principales: Cechova, Kristina, Lan, Chenyang, Macik, Matus, Barthes, Nicolas P. F., Jung, Manfred, Ulbrich, Maximilian H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629795/
https://www.ncbi.nlm.nih.gov/pubmed/34657173
http://dx.doi.org/10.1007/s00018-021-03963-y